Evaluation of Skin Sensitisation Risk of Polysiloxanes and Silanes

Exploring the skin sensitisation potential of functional polysiloxanes and silanes, the study leverages the SENS-IS assay - a 3D skin-based model. This method overcomes previous technical challenges related to solubility and composition, providing accurate results that align with in vivo outcomes. Thus, the SENS-IS assay is an effective starting point for integrated testing strategies for these substances.